Thursday, January 28, 2010

Pfizer Update

World’s largest pharmaceutical Pfizer has unveiled its research pipeline details after closing its $ 68 Billion deal; in the press conference released today Pfizer announced that out of the 500 different drug programs it will dump 100 drug programs from its portfolio. Eight of its NDA are there for approval which includes one new Estrogen formulation for menopause. Pfizer pipeline till date include

  • 30 drugs for cancer therapy
  • 20 drugs for Pain therapy
  • 10 drugs for Alzheimer’s disease
  • 5 Vaccine products
 Martin Mackay (Senior VP-Research) said that his partner Mikael Dolsten  said that they have developed a research and development integration concept completely different from other drug company, accordingly he will be looking after mass market drug and Dolsten will be handling protein medicines and vaccines and after the compounds have passed the proof of concept then clinical trials will be conducted by Pfizer's business unit.

Compounds included in its pipeline are

  • Prevnar, a vaccine against pneumococcal bacteria that cause brain and bloodstream infections (Next big thing after Lipitor)
  • Prevnar-13, for infants- $5 billion franchise by 2013-  awaiting FDA approval
  • Dolstein: Pfizer is trying it for pain and it is used against Staphylococcus aureus
  • A nerve growth factors blocker: first protein drug targeted against the sensation of pain


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