Big Sharks new trends....

Today night I slept around 9PM-IST and then got up at 12AM- IST to read something......then was checking out NASDAQ stock values over all there was up positive trend but for NASDAQ Biotech there was negative trend......what does it suggest?? Is it that Biotech opportunities are dwindling???.....What ever is the case but there is always a new start-up rolling up with new technology every now and then.....and the recent trend is many major pharma companies are forming alliances with these start-ups for drug discovery and ligand based companies for Mab's development and screening as these big sharks have drastically reduced their research spending to just 17% of their over all yearly spending and have rather started focusing on strategic acquisition to fill their pipeline for next cancer blockbuster therapy :)